Lactate Clearance for Assessing Response to Resuscitation in Severe Sepsis
نویسندگان
چکیده
منابع مشابه
Lactate Levels Can Guide Early Resuscitation Goals in Severe Sepsis Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy: A Randomized Clinical Trial
Background: The Surviving Sepsis Campaign international consensus guidelines recommend early resuscitation to optimize oxygen delivery. Although the best measure of oxygen delivery is debated, the published protocol utilized central venous oxygen saturation (ScvO2) of >70%. Serum lactate has been shown to prognosticate outcome, with higher levels being associated with worse morbidity and mortal...
متن کاملLactate is THE target for early resuscitation in sepsis
The resuscitation of patients in sepsis is a challenge for many reasons. One of the important questions is: Who needs what kind of resuscitation? In the present guidelines, resuscitation is mostly directed at patients with a high risk of mortality. In this review, I will discuss the value of using lactate levels to identify patients who might benefit from treatment and how to use sequential lac...
متن کاملEarly lactate clearance is associated with improved outcome in severe sepsis and septic shock.
OBJECTIVE Serial lactate concentrations can be used to examine disease severity in the intensive care unit. This study examines the clinical utility of the lactate clearance before intensive care unit admission (during the most proximal period of disease presentation) as an indicator of outcome in severe sepsis and septic shock. We hypothesize that a high lactate clearance in 6 hrs is associate...
متن کاملThe role of lactate clearance in the resuscitation bundle
The sepsis resuscitation bundle is the result of an effort on behalf of the Surviving Sepsis Campaign and the Institute for Healthcare Improvement to translate individual guideline recommendations into standardized, achievable goals for physicians caring for the critically ill patient. Implementation of this bundle is associated with decreased mortality. Many of the bundle items reflect compone...
متن کاملLactate Clearance Predicts Survival Among Patients in the Emergency Department with Severe Sepsis
INTRODUCTION Lactate clearance has been implicated as a predictor of mortality among emergency department (ED) patients with severe sepsis or septic shock. We aimed to validate prior studies showing that lactate clearance during the ED stay is associated with decreased mortality. METHODS Retrospective dual-centered cross-sectional study using patients identified in the Yale-New Haven Hospital...
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ژورنال
عنوان ژورنال: Academic Emergency Medicine
سال: 2013
ISSN: 1069-6563
DOI: 10.1111/acem.12179